Hereditary Cancer Test

Test

Know Your Risk for Inherited Cancers

If you have a family history of cancer, it’s possible that you inherited certain genetic mutations, or changes in the structure of your genes. Research has shown that some germline mutations lead to cancer. About 5-10% of all cancers are caused by such inherited mutations. Early detection of increased cancer risk leads to better health outcomes. 

What is Germline Genetic Testing?

Germline genetic testing is a form of precision medicine used to determine if you’re at increased risk for developing certain types of cancer. Commonly inherited cancers include breast, ovarian, gastrointestinal, colorectal, pancreatic, melanoma and prostate. 

Germline testing identifies inherited gene mutations like those in the BRCA1/2 genes. Variants of BRCA1/2 genes lead to increased risks of several cancers — most notably breast and ovarian cancer.

How is Germline Testing Done?

Testing for germline mutations is usually performed by a mouth saliva swab that is sent to a specialized lab for genetic testing. It usually takes just a few weeks to get the test results. Your provider will share your results and discuss what it means for you and your family. 

Who Can Benefit from Germline Genetic Testing?

Germline genetic testing can benefit adults of all ages who have an immediate family history of cancer or an at-risk ethnicity. Consider testing for hereditary cancer if you have an immediate family member with a history of:

  • Cancer diagnosed before age 50
  • Two or more types of cancer
  • Several close relatives diagnosed with the same type of cancer
  • Rare cancer types that are linked to genetic mutations
  • Ethnicity linked to increased risk of certain inherited cancers 

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