Liver Disease


About Liver Disease

Your liver is the largest solid organ in your body, and it’s responsible for helping digest food, storing energy and removing poisons. If it becomes diseased or injured, the consequences can be significant and may even lead to liver failure. Liver disease is a broad term that describes any potential disturbance of liver function. Generally, more than 75% or 3/4 of your liver needs to be affected before its function is decreased.

Symptoms of Liver Disease

Sometimes people with liver disease don’t have any noticeable symptoms. There are imaging tests, liver function tests and tissue analysis (biopsy) to check for liver damage and help diagnose liver disease. Signs of liver damage can vary but may include:

  • Swelling of your abdomen and legs
  • Bruising easily
  • Changes in the color of your stool or urine
  • Jaundice (yellowing of your skin and eyes)
  • Weakness and fatigue
  • Weight loss
  • Nausea and vomiting
  • Gastrointestinal bleeding
  • Mental confusion

Types and Causes of Liver Disease

Alcohol & Cirrhosis

Drinking too much alcohol can lead to fatty liver, alcoholic hepatitis and cirrhosis of the liver, which involves the loss of liver cells and irreversible scarring. Alcohol abuse is the most common cause of liver disease in North America.

Drug-induced Liver Disease

Excessive amounts of acetaminophen (pain reliever) can cause acute liver damage.

Fatty Liver Disease

Fatty liver disease is a condition that builds up fat in your liver. There are two types: nonalcoholic due to obesity and alcoholic.


Hepatitis A, B, C, D and E are viral infections that cause liver disease and inflammation of your liver. If your liver is inflamed, it may not work properly.

Toxic Mushroom Ingestion

Excessive iron in the liver (hereditary) and excessive copper in the liver (Wilson’s disease) can also lead to liver disease.

Stages of Liver Failure

Liver failure can occur suddenly (rare) or over the course of several years. It’s a life-threatening condition that requires immediate medical care. The first signs of liver failure may include nausea, confusion, fatigue, diarrhea and loss of appetite. Since those symptoms can be associated with a number of other health conditions, it can be difficult to tell that your liver is failing.

As the failure progresses, you’ll notice more serious symptoms like confusion, feeling disoriented and extreme sleepiness. Coma and even death are possible.

Treatment for Liver Disease

If you’re experiencing liver failure, your Mercy care team will do everything we can to save the part of your liver that’s still working. If that’s not possible, you may need to have a liver transplant.

Treatment for liver disease depends on the type and severity of your diagnosis. Sometimes, lifestyle modifications like losing weight or stopping alcohol can help. In other cases, you may need medications or even surgery.

If you have concerns about liver disease, talk with your primary care provider. He or she can help determine if you’re experiencing liver disease and what may have caused it, and refer you to a gastroenterologist for more specialized care if needed.

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