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Although pancreatic cancer affects far fewer people than other types of cancer, it’s still a leading cause of cancer death. You can take steps to reduce your overall risk of pancreatic cancer. By talking to your Mercy doctor as soon as you experience unusual pain, you can increase your chances of catching pancreatic cancer before it spreads to other parts of your body.
Pancreatic cancer is a very aggressive form of digestive cancer. If cells within your pancreas begin to grow abnormally, they can form a cancerous tumor. According to the American Cancer Society, the average lifetime risk of someone developing pancreatic cancer is about 1 in 64.
Many people who have pancreatic cancer don’t show outward symptoms until their cancer has already spread beyond the pancreas. The sooner you begin treatment for pancreatic cancer, the greater your chances of survival.
There are two main types of cells within your pancreas: exocrine cells and endocrine cells. Each cell type can form its own type of cancer with its own risk factors, symptoms, diagnostic methods, treatments and therapies.
Exocrine cancer forms in the exocrine cells, which is where enzymes that help digest food are made. Exocrine pancreatic cancers make up about 95% of all cancers of the pancreas. There are many types including:
On rare occasions, pancreatic cancer can develop in the endocrine cells, which are responsible for making and releasing hormones into the bloodstream. This type of cancer is known as a pancreatic neuroendocrine tumor or pancreatic NET. Pancreatic NETs are managed differently than exocrine pancreatic cancers. If you develop one of these tumors, your Mercy doctor will discuss your treatment options with you.
While the exact cause of pancreatic cancer isn’t known, cancers can be caused by DNA changes that turn on and off the genes that help cells grow, divide and stay alive. People can inherit certain gene mutations from their parents which increases their risk of developing pancreatic cancer.
Men are slightly more likely to develop pancreatic cancer than women. This may be due to higher tobacco use, which raises their risk. The risk of pancreatic cancer increases as we age. Nearly all patients of pancreatic cancer are older than age 45, and the average age of diagnosis is 70.
The risk of contracting pancreatic cancer is nearly two times as high among smokers compared to non-smokers. Nearly one-fourth of all pancreatic cancers are thought to be caused by tobacco use.
People who are obese or overweight are thought to be 20% more likely to be diagnosed with pancreatic cancer.
Increased exposure to workplace chemicals, specifically used in dry cleaning or metalworking industries, may make a person more susceptible to pancreatic cancer. Gene mutations can develop as a result of exposure to these cancer-causing chemicals, and be passed down from generation to generation.
People who have a history of heavy alcohol or tobacco use may develop chronic pancreatitis, long-term inflammation of the pancreas, which carries with it an increased risk of pancreatic cancer.
Inherited gene mutations can pass from generation to generation. Some of these mutations cause as many as 10% of pancreatic cancers.
Signs of pancreatic cancer don’t usually develop until cancer has advanced, spreading to other parts of the body. The signs and symptoms of pancreatic cancer can vary depending on the type of pancreatic tumor present. See your Mercy doctor if you are experiencing symptoms that persist or don’t get better over time.
Exocrine pancreatic symptoms include:
Symptoms of pancreatic neuroendocrine tumors (NETs) can vary but may include:
Finding out you have cancer can be a frightening and overwhelming experience. That’s why Mercy’s cancer team offers more than just medical treatments for its patients. We’ll help you fully understand your condition and your options for treatment and therapy. That way, you can make thoughtful, well-informed decisions about your cancer care. The sooner you begin treatment for pancreatic cancer, the greater your chances of survival.
Tumors in the pancreas are usually too small for doctors to feel during a physical exam, which means they might not be found until they’ve spread beyond the pancreas. Mercy gastroenterologists, pathologists and radiologists use advanced diagnostic testing methods to help detect pancreatic cancer, evaluate the extent of the disease and develop a treatment plan.
Imaging tests may be done both before and after a pancreatic cancer diagnosis for a number of reasons such as looking for suspicious areas that might be cancer, determining how far cancer might have spread, and looking for signs of cancer returning after treatment. Common imaging procedures include:
There are several blood and laboratory tests that can be used to help diagnose pancreatic cancer as well as help determine the best course of treatment(s) if cancer is found.
A biopsy is generally required for a definitive diagnosis of pancreatic cancer. A biopsy is when cells or tissues are removed to be examined by a pathologist for signs of cancer.
At Mercy, we don’t just care for you, we care about you. We’ll do everything we can to help you battle your pancreatic cancer, relieve your symptoms and ease your mind. Your treatment plan will depend on several factors: what stage your cancer is in and whether it’s already spread to other areas of your body. You may need one or more types of treatment, which can include surgery, radiation therapy, chemotherapy, targeted therapy & immunotherapy.
In most cases, surgery is the best treatment for pancreatic cancer that hasn’t spread beyond the pancreas. Mercy gastrointestinal surgeons are skilled in using the latest surgical procedures and techniques, such as minimally invasive laparoscopic surgery, robotic surgery and endoscopic surgery. There are many different kinds of pancreatic cancer surgeries, but which kind you need depends on many factors. The types of pancreatic surgery include the following.
Also known as a Whipple procedure, this is the most common type of surgery for pancreatic cancer and is used to remove cancer in the head of the pancreas. Most often this surgery is done with an incision down the belly, but it’s sometimes performed laparoscopically.
Distal & Total Pancreatectomy
In a distal pancreatectomy, your Mercy surgeon removes just the tail of your pancreas, and may even remove your spleen as well. If your cancer has spread throughout the pancreas, but can still be removed, your Mercy surgeon may recommend a total pancreatectomy. In this procedure, your entire pancreas is removed, as well as your gallbladder, part of your stomach, intestines and spleen.
A stent is a small tube made of metal, which is sometimes placed inside a blocked bile duct to keep it open. This is the most common approach to relieving a blocked bile duct and is usually performed during an endoscopy.
Another option for relieving a blocked bile duct is bypass surgery, which reroutes the flow of bile from the common bile duct into the small intestine. This procedure can be performed laparoscopically or by making a large cut in the abdomen.
Palliative surgery for pancreatic cancer is usually performed if the cancer is too widespread to be removed completely. It can be performed using an operation known as bypass surgery to relieve symptoms or prevent complications.
If surgery isn’t an option for you, our radiation oncologists offer advanced radiation therapy treatments to precisely target cancerous tumors. Radiation therapy can be used in all stages of pancreatic cancer, including:
External Beam Radiation
External beam radiation is the most common type of radiation therapy used to treat pancreatic cancer. It focuses radiation from a source outside of the body onto the area of the tumor. In addition to standard external beam radiation, two forms of planning and delivering external beam radiation therapy may be used to treat pancreatic cancer:
Chemotherapy (also referred to as “chemo”) uses drugs delivered directly into your veins or given by mouth to reach pancreatic cancer cells throughout the body. Chemo may be an option for some patients before, after or in lieu of surgery. It’s usually given in cycles, with periods of time built into treatment plans that allow for patients to recover fully.
Your surgeon will help you understand what to expect from your operation or treatment plan, and help you outline a unique care plan for your recovery.
At Mercy, we offer comprehensive testing services to diagnose all types of pancreatic cancer, including:
At Mercy, we offer compassionate care for a variety of cancer treatment services, including:
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